Determinism and Medicine

A few days ago, I finished my first semester as a medical student. Initially, despite my hardest efforts, I struggled. As I got into the flow of studied, my marks and attitude vastly improved. Of this fact, I am very proud. I met a challenge, adapted out of necessity, and carried on without incident.

The terrifying part of the matter is that the whole ordeal seems like a large, almost homogenous blur. It is a very vivid blur, but the jumble of terms and concepts that I now know so very well are not neatly organized into chronological order. I feel like I simply know all we learned for the first semester. I describe it as terrifying because that 4-month stretch of my life is seemingly unaccounted for; I am wiser and more erudite as a result, but the intensity at which I studied left little time for taking conscious snapshots of times and places.

I’m not saying I can’t remember anything. When I press myself, I remember going to the beach, cooking for the South Asian Student Society food sale, etc. But largely, I feel like I’ve become a being of the present. I am enjoying a few stress free days of break and gearing up for the consequent grueling semester ahead of me.

Moreover, I don’t know if I like this change. I feel almost like a passive observer, sometimes going through the motions of studying, relaxing, etc. because there truly is no other choice than to do these things at the deemed times. I know that this is how society operates in general; people have schedules and shift work where they may cover certain time spans and go home for a certain time spans and rinse repeat until they are old and their lives lived.

These thoughts have reminded me of another association I was making in my head – the general feeling of determinism in medicine. I’ve described my personal feelings on this as they relate to my studies above, but this tangentially ties into a greater concept regarding the nature of medicine. Everything is so intricately cataloged and supposedly explained that that there is little room for deviation. While this makes medicine an exact science, it mildly takes away some of spontaneity of life. People will always break their carpal bones and commonly fracture their scaphoid, women will always become pregnant as a result of several cascading processes involving fertilization and hormonal secretions, the median lobe of the prostate will always give benign hypertrophy, etc.

Everything is categorized and divided into deterministic events that are going to happen. And I know, of course, that the median lobe of the prostate can on rare occasions give rise to malignant cancer, but my point generally is that, on the whole, now that I am starting to have a good understanding of the human body, it feels like everyone has some pending doom over their heads waiting to be played out, echoing what I’ve learned in my classes and from my textbooks.

Similarly, as I know I will learn later, I will be given deterministic measures for how each of these scenarios will play out. For instance, I will later learn how long a break in the arm will take to heal, how it will respond to different conditions, etc. This adds to the sense that these events will happen and I will feel obligated to treat them in an exact way; otherwise I will be offering my faceless, nameless patients sub-optimal recovery.

Another aspect of this is the way physicians are educated to handle patients and think about them. Patients are categorized into broad frameworks that involve their personality types, the number of kids they have, and their occupation. Is it so simple to define an individual by these common themes? I know it is necessary, but I empathize and would feel strange knowing a doctor was thinking of me in such terms. In our book on the patient interview, we are taught that analyzing responses to phrases physicians say is a good method to gauge how a patient is feeling. There is a significant deal of psychology in that book, but my point overall here is that our instruction is so precise that we are taught even social interaction. There again is that deterministic feel; there is a list of scripted patient responses and a list of replies for each in every scenario given. Every interaction can be predicted and optimally responded-to in order to ensure patient compliance and satisfaction

I think, especially with that last piece about the patient interview, physicians are explicitly trained to follow established protocols; this casts a sense of looming inevitability and determinism about the whole discipline. There is always something a physician is “supposed to do” in order to properly provide care. This is why, more than anything else, I am interested in research. It provides that lacking element of creativity and flexibility to an otherwise rigid practice.

So, that was more of a rant about the confines of medicine and the way its material is presented.

Haven’t posted in a while. It’s not that I’ve been busy – I just haven’t had the impetus to do so.

ICC pictures have come out much better lately now that I put in some serious time into learning how to use the advanced microscope at PBRC. Also, during my last experiment  we observed spontaneous formation of red cells in one of the wells. My mentor says they probably are erythroid cells. Naturally, we’re repeating the protocol (involving the directed temporal manipulation of the canonical Wnt signalling pathway). Here are some HES cells stained fro DAPI and β-actin after undergoing a cardiomyocyte differentiation.DAPI and  β-actinOtherwise, I’ve been watching (and re-watching) lots of movies and listening to more audiobooks lately. I watched 127 hours yesterday with my parents. The movie was very stressful to watch. Here’s a list of movies I’ve recently seen:

  • There Will Be Blood
  • Moon
  • The Assassination of Jesse James by the Coward Robert Ford
  • No Country for Old Men
  • A Serious Man
  • Fargo
  • O Brother Where Art Thou
  • Synecdoche, New York
  • Batman The Dark Knight Returns
  • 127 Hours
  • Eastern Promises
  • Mary and Max
  • Burn After Reading

There are a few more I’d like to see. I listened to Outliers, Tipping Point, and currently am listening to Blink! all by Malcolm Gladwell, whose unfettered prose makes for good narration.

I also had my mid-term for my Biophysics class. It wasn’t particularly difficult – 10 questions, all short answer. There wasn’t anything I struggled with. I’d be surprised if I got less than a 95 on it.

I have a presentation next week for my Chemistry of Proteins class regarding protein-ligand interactions, so its preparation will occupy most of my time this weekend. I have to give a detailed explanation of three techniques used to quantify this. I’ve found two – ELISA (which I do), and ITC. Looking for number there after this post.

As far at strength and nutrition go, I’m trying something new – attempting to gain weight. The goal is to end at around 165-170 lbs. I’m staying fairly consistent with training and whatnot. The most important thing is to log everything so as to understand what works with my body. It’s an interesting process – eating more and trying not to feel guilty, but the best part is that it is entirely controlled and meticulously documented.